Anti-Human HCRTR2 Polyclonal Antibody (HD507014)

Name: Anti-Human HCRTR2 Polyclonal Antibody
Brand: abinScience
SKU: HD507014
Price: 168 USD
Availability: InStock

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사양:

50ug
100ug

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HD507014

설명

Anti-Human HCRTR2 Polyclonal Antibody (HD507014) is a rabbit polyclonal antibody detecting HCRTR2. Suitable for Human.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human HCRTR2 (Ser2-Glu54&Glu192-Met222&Leu367-Trp444).

타겟

HCRTR2, Hypocretin receptor type 2, ORXR2, OX2R, OXR2, Orexin receptor type 2, Ox-2-R, Ox2-R, Ox2R

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

O43614

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

Orexin receptor type 2 (HCRTR2) is a ~50 kDa protein. G-protein coupled receptor that binds neuropeptides orexin-A and orexin-B, two neuropeptides derived from a common precursor, prepro-orexin. Upon neuropeptide ligand binding, HCRTR2 can couple with both G(q)/11 and G(i)/o heterotrimeric G-proteins thereby initiating distinct downstream signaling cascades. Involved in regulating the sleep-wake cycle. Contributes to central regulation of glucose homeostasis.

1. Yin, J. et al. (2016) Nature structural & molecular biology 23, 293-9. PMID: 26950369

2. Hong, C. et al. (2021) Nature communications 12, 815. PMID: 33547286

3. Yin, J. et al. (2022) Nature communications 13, 2902. PMID: 35614071

4. Sakurai, T. et al. (1998) Cell 92, 573-85. PMID: 9491897

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-Human HCRTR2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human HCRTR2 Polyclonal Antibody (HD507014)

개요

이미지

참고 문헌

데이터시트

SDS