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Anti-Human IGF-I/IGF-1 Recombinant Antibody (SAA0432) (HY095107)

Anti-Human IGF-I/IGF-1 Recombinant Antibody (SAA0432)
Anti-Human IGF-I/IGF-1 Recombinant Antibody (SAA0432)
Anti-Human IGF-I/IGF-1 Recombinant Antibody (SAA0432)
Anti-Human IGF-I/IGF-1 Recombinant Antibody (SAA0432)
Anti-Human IGF-I/IGF-1 Recombinant Antibody (SAA0432)
Anti-Human IGF-I/IGF-1 Recombinant Antibody (SAA0432)
가격(USD):
사양:
  • 50ug
  • 100ug
수량:
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  • 개요

  • 이미지

  • 참고 문헌

  • 데이터시트

  • SDS

개요
카탈로그 번호HY095107
종 반응성Human
응용 분야ELISA, FCM, WB
숙주 종Mouse
클론성Monoclonal
이소타입IgG2a, kappa
클론 IDSAA0432
테스트된 응용 분야 WB
타겟 IGF-I, IGF1, Mechano growth factor, MGF, Insulin-like growth factor I, IBP1, Somatomedin-C
내독소 수준 Please contact with the lab for this information.
순도 >95% as determined by SDS-PAGE.
정제 Protein A/G purified from cell culture supernatant.
등록번호 P05019
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 0.09% Sodium azide.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
배경

Insulin-like growth factor 1 (IGF1) is a ~21 kDa protein. The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exocytosis of IGF1 is required for sensory perception of smell in the olfactory bulb.

1. Zoidis, E. et al. (2011) Molecular and cellular biochemistry 348, 33-42. PMID: 21076856
2. Shcheglovitov, A. et al. (2013) Nature 503, 267-71. PMID: 24132240
3. Saegusa, J. et al. (2009) The Journal of biological chemistry 284, 24106-14. PMID: 19578119
4. Fujita, M. et al. (2012) The Journal of biological chemistry 287, 12491-500. PMID: 22351760
5. Fujita, M. et al. (2013) The Journal of biological chemistry 288, 3059-69. PMID: 23243309
6. Fujita, M. et al. (2013) The Journal of biological chemistry 288, 19593-603. PMID: 23696648
참고사항 For research use only.
이미지
  • Anti-Human IGF-I/IGF-1 Recombinant Antibody (SAA0432)

    SDS-PAGE

    SDS-PAGE for Anti-Human IGF1 Antibody (SAA0432)

  • Anti-Human IGF-I/IGF-1 Recombinant Antibody (SAA0432)

    Bioactivity

    Detects recombinant human IGF1 (Catalog No: HY095011) in indirect ELISA

  • Anti-Human IGF-I/IGF-1 Recombinant Antibody (SAA0432)

    Western blot

    Western blot analysis was performed using anti-/ monoclonal antibody at 1ug/mL on various samples.
    Lane 1: ATGE3001 200ng
    Lane 2: 1* loading buffer

참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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