Anti-Human ING4 Polyclonal Antibody (HP148014)

Name: Anti-Human ING4 Polyclonal Antibody
Brand: abinScience
SKU: HP148014
Price: 168 USD
Availability: InStock

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개요
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SDS

개요

카탈로그 번호

HP148014

설명

Anti-Human ING4 Polyclonal Antibody (HP148014) is a rabbit polyclonal antibody detecting ING4 in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, and Chicken.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human ING4 (Met1-Lys127).

타겟

ING4, Inhibitor of growth protein 4, p29ING4

정제

Purified by antigen affinity column.

등록번호

Q9UNL4

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Inhibitor of growth protein 4 (ING4) is a ~28 kDa protein. Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4. Through chromatin acetylation it may function in DNA replication. May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation. Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA. May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC.

1. Doyon, Y. et al. (2006) Molecular cell 21, 51-64. PMID: 16387653

2. Zhang, X. et al. (2004) FEBS letters 570, 7-12. PMID: 15251430

3. Kim, S. et al. (2004) Proceedings of the National Academy of Sciences of the United States of America 101, 16251-6. PMID: 15528276

4. Garkavtsev, I. et al. (2004) Nature 428, 328-32. PMID: 15029197

5. Ozer, A. et al. (2005) Proceedings of the National Academy of Sciences of the United States of America 102, 7481-6. PMID: 15897452

참고사항

For research use only.

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참고 문헌

데이터시트

Anti-Human ING4 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human ING4 Polyclonal Antibody (HP148014)

개요

이미지

참고 문헌

데이터시트

SDS