Anti-Human ING4 Recombinant Antibody (SAA1725) (HP148013)

Name: Anti-Human ING4 Recombinant Antibody (SAA1725)
Brand: abinScience
SKU: HP148013
Price: 196 USD
Availability: InStock

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100ug
1mg

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HP148013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1725

Clonality

Monoclonal

Target

ING4, Inhibitor of growth protein 4, p29ING4

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9UNL4

RRID

Anti-Human ING4 Antibody (SAA1725) (abinScience Cat# HP148013, RRID:AB_3727486)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Inhibitor of growth protein 4 (ING4) is a ~28 kDa protein. Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4. Through chromatin acetylation it may function in DNA replication. May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation. Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA. May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC.

1. Doyon, Y. et al. (2006) Molecular cell 21, 51-64. PMID: 16387653

2. Zhang, X. et al. (2004) FEBS letters 570, 7-12. PMID: 15251430

3. Kim, S. et al. (2004) Proceedings of the National Academy of Sciences of the United States of America 101, 16251-6. PMID: 15528276

4. Garkavtsev, I. et al. (2004) Nature 428, 328-32. PMID: 15029197

5. Ozer, A. et al. (2005) Proceedings of the National Academy of Sciences of the United States of America 102, 7481-6. PMID: 15897452

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human ING4 Antibody (SAA1725)

References

Datasheet

Anti-Human ING4 Recombinant Antibody (SAA1725).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human ING4 Recombinant Antibody (SAA1725) (HP148013)

Overview

Images

References

Datasheet

SDS

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