中文
English
한국어
日本語
Español
Français
Русский
| 카탈로그 번호 | HV737013 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Human | ||||
| 응용 분야 | ELISA | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a, kappa | ||||
| 클론 ID | SAA1623 | ||||
| 타겟 | Renal carcinoma antigen NY-REN-64, IRAK-4, IRAK4, Interleukin-1 receptor-associated kinase 4 | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | Q9NWZ3 | ||||
| RRID | Anti-Human IRAK4 Antibody (SAA1623) (abinScience Cat# HV737013, RRID:AB_3727384) |
||||
| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
||||
| 제품 사용 정보 |
| ||||
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Interleukin-1 receptor-associated kinase 4 (IRAK4) is a ~51 kDa protein. Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation to form the Myddosome together with IRAK2. Phosphorylates initially IRAK1, thus stimulating the kinase activity and intensive autophosphorylation of IRAK1. Phosphorylates E3 ubiquitin ligases Pellino proteins (PELI1, PELI2 and PELI3) to promote pellino-mediated polyubiquitination of IRAK1. 1. Hoarau, C. et al. (2007) Journal of immunology (Baltimore, Md. : 1950) 179, 4754-65. PMID: 17878374 | ||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Human IRAK4 Antibody (SAA1623)
+86-027-65523339
중국 우한시 심둔사로 666번지 C동, 우한, 430206
