

| 카탈로그 번호 | HV505014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human LAMP3 Polyclonal Antibody (HV505014) is a rabbit polyclonal antibody detecting Lysosome-associated membrane glycoprotein 3; LAMP-3; Lysosomal-associated membrane protein 3; DC-lysosome-associated membrane glycoprotein; DC LAMP; Protein TSC403; CD208; LAMP3; DCLAMP; TSC403 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant human LAMP3 (Ser222-Cys376). | ||||||||
| 타겟 | Lysosome-associated membrane glycoprotein 3; LAMP-3; Lysosomal-associated membrane protein 3; DC-lysosome-associated membrane glycoprotein; DC LAMP; Protein TSC403; CD208; LAMP3; DCLAMP; TSC403 | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q9UQV4 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Lysosome-associated membrane glycoprotein 3 (LAMP3) is a ~44 kDa protein. Lysosomal membrane glycoprotein which plays a role in the unfolded protein response (UPR) that contributes to protein degradation and cell survival during proteasomal dysfunction. Plays a role in the process of fusion of the lysosome with the autophagosome, thereby modulating the autophagic process. Promotes hepatocellular lipogenesis through activation of the PI3K/Akt pathway. May also play a role in dendritic cell function and in adaptive immunity. 1. Dominguez-Bautista, JA. et al. (2015) European journal of cell biology 94, 148-61. PMID: 25681212 2. Nagelkerke, A. et al. (2014) Endocrine-related cancer 21, 101-12. PMID: 24434718 3. Liao, X. et al. (2018) Molecular and cellular endocrinology 470, 160-167. PMID: 29056532 4. de Saint-Vis, B. et al. (1998) Immunity 9, 325-36. PMID: 9768752 | ||||||||
| 참고사항 | For research use only |
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