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| 카탈로그 번호 | HC410013 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Human | ||||
| 응용 분야 | ELISA | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a, kappa | ||||
| 클론 ID | SAA1797 | ||||
| 타겟 | Transforming growth factor beta-1-binding protein 1, Latent-transforming growth factor beta-binding protein 1, LTBP-1, LTBP1, TGF-beta1-BP-1 | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | Q14766 | ||||
| RRID | Anti-Human LTBP1 Antibody (SAA1797) (abinScience Cat# HC410013, RRID:AB_3727559) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Latent-transforming growth factor beta-binding protein 1 (LTBP1) is a ~186 kDa protein. Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta. Outcompeted by LRRC32/GARP for binding to LAP regulatory chain of TGF-beta. 1. Miyazono, K. et al. (1991) The EMBO journal 10, 1091-101. PMID: 2022183 2. Saharinen, J. et al. (1996) The EMBO journal 15, 245-53. PMID: 8617200 3. Gleizes, PE. et al. (1996) The Journal of biological chemistry 271, 29891-6. PMID: 8939931 4. Annes, JP. et al. (2004) The Journal of cell biology 165, 723-34. PMID: 15184403 5. Wang, R. et al. (2012) Molecular biology of the cell 23, 1129-39. PMID: 22278742 | ||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Human LTBP1 Antibody (SAA1797)
+86-027-65523339
중국 우한시 심둔사로 666번지 C동, 우한, 430206
