中文
English
한국어
日本語
Español
Français
Русский
| 카탈로그 번호 | HW297013 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Human | ||||
| 응용 분야 | ELISA | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a, kappa | ||||
| 클론 ID | SAA1840 | ||||
| 타겟 | MAGEA6, Cancer/testis antigen 1.6, MAGE6, MAGE3B antigen, MAGE-6 antigen, CT1.6, Melanoma-associated antigen 6 | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | P43360 | ||||
| RRID | Anti-Human MAGEA6 Antibody (SAA1840) (abinScience Cat# HW297013, RRID:AB_3727603) |
||||
| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
||||
| 제품 사용 정보 |
| ||||
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Melanoma-associated antigen 6 (MAGEA6) is a ~34 kDa protein. Activator of ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases that acts as a repressor of autophagy. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. 1. Yang, B. et al. (2007) Cancer research 67, 9954-62. PMID: 17942928 2. Doyle, JM. et al. (2010) Molecular cell 39, 963-74. PMID: 20864041 3. Ravichandran, R. et al. (2019) EMBO reports 20, e47352. PMID: 31267705 | ||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Human MAGEA6 Antibody (SAA1840)
+86-027-65523339
중국 우한시 심둔사로 666번지 C동, 우한, 430206
