Anti-Human MC3R Polyclonal Antibody (HC053014)

Name: Anti-Human MC3R Polyclonal Antibody
Brand: abinScience
SKU: HC053014
Price: 168 USD
Availability: InStock

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개요
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개요

카탈로그 번호

HC053014

설명

Anti-Human MC3R Polyclonal Antibody (HC053014) is a rabbit polyclonal antibody detecting Melanocortin receptor 3; MC3-R; MC3R in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant human MC3R (Asn2-Gln37&Val101-Asn118&Arg302-Gly323).

타겟

Melanocortin receptor 3; MC3-R; MC3R

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

P41968

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Melanocortin receptor 3 (MC3R) is a ~36 kDa protein. G protein-coupled receptor for melanocyte-stimulating hormones (alpha, beta, and gamma-MSH) and corticotropin/ACTH, which are peptide products of the POMC precursor. Upon activation, couples to G(s) protein, stimulating adenylate cyclase and the cAMP-dependent signaling pathway, which contributes to the regulation of energy homeostasis. Required for expression of anticipatory patterns of activity and wakefulness during periods of limited nutrient availability and for the normal regulation of circadian clock activity in the brain. Binding of the Agouti-related protein/AGPR antagonist precludes alpha-MSH-induced signaling, blocking cAMP production.

1. Feng, W. et al. (2023) Cell discovery 9, 81. PMID: 37524700

2. Gantz, I. et al. (1993) The Journal of biological chemistry 268, 8246-50. PMID: 8463333

3. Mencarelli, M. et al. (2008) European journal of human genetics : EJHG 16, 581-6. PMID: 18231126

4. Ollmann, MM. et al. (1997) Science (New York, N.Y.) 278, 135-8. PMID: 9311920

참고사항

For research use only

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참고 문헌

데이터시트

Anti-Human MC3R Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human MC3R Polyclonal Antibody (HC053014)

개요

이미지

참고 문헌

데이터시트

SDS