

| 카탈로그 번호 | HA153014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human MCIDAS Polyclonal Antibody (HA153014) is a rabbit polyclonal antibody detecting McIdas protein in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human MCIDAS (Thr314-Ser385). | ||||||||
| 타겟 | Multicilin, Multiciliate differentiation and DNA synthesis-associated cell cycle protein, McIdas protein, Protein Idas, MCIDAS, IDAS, MCI, MCIN | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | D6RGH6 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Multicilin (MCIDAS) is a ~41 kDa protein. Transcription regulator specifically required for multiciliate cell differentiation. Acts in a multiprotein complex containing E2F4 and E2F5 that binds and activates genes required for centriole biogenesis. Required for the deuterosome-mediated acentriolar pathway. Plays a role in mitotic cell cycle progression by promoting cell cycle exit. Modulates GMNN activity by reducing its affinity for CDT1. 1. Boon, M. et al. (2014) Nature communications 5, 4418. PMID: 25048963 2. Pefani, DE. et al. (2011) The Journal of biological chemistry 286, 23234-46. PMID: 21543332 3. Caillat, C. et al. (2013) The Journal of biological chemistry 288, 31624-34. PMID: 24064211 | ||||||||
| 참고사항 | For research use only. |
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