Anti-Human MCM3AP Polyclonal Antibody (HD528014)

Name: Anti-Human MCM3AP Polyclonal Antibody
Brand: abinScience
SKU: HD528014
Price: 168 USD
Availability: InStock

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사양:

50ug
100ug

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HD528014

설명

Anti-Human MCM3AP Polyclonal Antibody (HD528014) is a rabbit polyclonal antibody detecting MCM3AP. Suitable for Human and Mouse.

Highlights

●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human MCM3AP (Thr602-Gly969).

타겟

80 kDa MCM3-associated protein, EC:2.3.1.-, EC:2.3.1.48, GANP, Germinal-center associated nuclear protein, KIAA0572, MAP80, MCM3 acetylating protein, MCM3 acetyltransferase, MCM3AP

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

O60318

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

Germinal-center associated nuclear protein (MCM3AP) is a ~218 kDa protein. As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores. Through the acetylation of histones, affects the assembly of nucleosomes at immunoglobulin variable region genes and promotes the recruitment and positioning of transcription complex to favor DNA cytosine deaminase AICDA/AID targeting, hence promoting somatic hypermutations.

1. Wickramasinghe, VO. et al. (2010) Current biology : CB 20, 25-31. PMID: 20005110

2. Okamoto, N. et al. (2010) Genes to cells : devoted to molecular & cellular mechanisms 15, 471-84. PMID: 20384790

3. Jani, D. et al. (2012) Nucleic acids research 40, 4562-73. PMID: 22307388

4. Umlauf, D. et al. (2013) Journal of cell science 126, 2656-67. PMID: 23591820

5. Singh, SK. et al. (2013) Nature communications 4, 1830. PMID: 23652018

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-Human MCM3AP Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human MCM3AP Polyclonal Antibody (HD528014)

개요

이미지

참고 문헌

데이터시트

SDS