Anti-Human MIF Recombinant Antibody (SAA0115), APC (HB816137)

Name: Anti-Human MIF Recombinant Antibody (SAA0115), APC
Brand: abinScience
SKU: HB816137
Price: 290 USD
Availability: InStock

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참고 문헌
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개요

카탈로그 번호	HB816137
종 반응성	Human
응용 분야	FCM
숙주 종	Human
클론성	Monoclonal
이소타입	IgG1, kappa
클론 ID	SAA0115
접합	APC
타겟	MIF, L-dopachrome isomerase, L-dopachrome tautomerase, GIF, Macrophage migration inhibitory factor, MMIF, Phenylpyruvate tautomerase, Glycosylation-inhibiting factor, GLIF
내독소 수준	Please contact with the lab for this information.
관련 제품	Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10), APC
등록번호	P14174
형태	Liquid
저장 완충액	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Store at 4°C for 12 months. Protect from light. Do not freeze.
배경	Macrophage migration inhibitory factor (MIF/GIF) is a ~12 kDa protein. Pro-inflammatory cytokine involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity. 1. Oddo, M. et al. (2005) Infection and immunity 73, 3783-6. PMID: 15908412 2. Emonts, M. et al. (2007) Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 44, 1321-8. PMID: 17443469 3. Fan, C. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 10994-9. PMID: 23776208 4. Tan, TH. et al. (2001) The Biochemical journal 357, 373-83. PMID: 11439086
참고 문헌	1. Stamps SL, et al. Mechanism of the phenylpyruvate tautomerase activity of macrophage migration inhibitory factor: properties of the P1G, P1A, Y95F, and N97A mutants. Biochemistry. 2000 Aug 15;39(32):9671-8.8 [HB816137]
참고사항	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.