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| 카탈로그 번호 | HP852013 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Human | ||||
| 응용 분야 | ELISA | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a, kappa | ||||
| 클론 ID | SAA1731 | ||||
| 타겟 | Motile sperm domain-containing protein 2, MOSPD2 | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | Q8NHP6 | ||||
| RRID | Anti-Human MOSPD2 Antibody (SAA1731) (abinScience Cat# HP852013, RRID:AB_3727492) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Motile sperm domain-containing protein 2 (MOSPD2) is a ~59 kDa protein. Endoplasmic reticulum-anchored protein that mediates the formation of contact sites between the endoplasmic (ER) and endosomes, mitochondria or Golgi through interaction with conventional- and phosphorylated-FFAT-containing organelle-bound proteins. In addition, forms endoplasmic reticulum (ER)-lipid droplets (LDs) contacts through a direct protein-membrane interaction and participates in LDs homeostasis. The attachment mechanism involves an amphipathic helix that has an affinity for lipid packing defects present at the surface of LDs. Promotes migration of primary monocytes and neutrophils, in response to various chemokines. 1. Di Mattia, T. et al. (2018) EMBO reports 19. PMID: 29858488 2. Di Mattia, T. et al. (2020) The EMBO journal 39, e104369. PMID: 33124732 3. Zouiouich, M. et al. (2022) The Journal of cell biology 221. PMID: 35389430 4. Mendel, I. et al. (2017) Journal of immunology (Baltimore, Md. : 1950) 198, 2125-2132. PMID: 28137892 | ||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Human MOSPD2 Antibody (SAA1731)
+86-027-65523339
중국 우한시 심둔사로 666번지 C동, 우한, 430206
