Anti-Human OS9 Polyclonal Antibody (HC357014)

Name: Anti-Human OS9 Polyclonal Antibody
Brand: abinScience
SKU: HC357014
Price: 168 USD
Availability: InStock

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개요
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개요

카탈로그 번호

HC357014

설명

Anti-Human OS9 Polyclonal Antibody (HC357014) is a rabbit polyclonal antibody detecting OS9 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human OS9 (Asn32-Gln251).

타겟

Protein OS-9, OS9, Amplified in osteosarcoma 9

정제

Purified by antigen affinity column.

등록번호

Q13438

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Protein OS-9 (OS9) is a ~75 kDa protein. Lectin component of the HRD1 complex, which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD). Specifically recognizes and binds improperly folded glycoproteins as well as hyperglycosylated proteins, retain them in the ER, and transfers them to the ubiquitination machinery and promote their degradation. Possible targets include TRPV4 as well as hyperglycosylated HSP90B1.

1. Christianson, JC. et al. (2008) Nature cell biology 10, 272-82. PMID: 18264092

2. Bernasconi, R. et al. (2008) The Journal of biological chemistry 283, 16446-54. PMID: 18417469

3. Alcock, F. et al. (2009) Journal of molecular biology 385, 1032-42. PMID: 19084021

4. Hosokawa, N. et al. (2009) The Journal of biological chemistry 284, 17061-17068. PMID: 19346256

5. Satoh, T. et al. (2010) Molecular cell 40, 905-16. PMID: 21172656

6. Dersh, D. et al. (2014) Molecular biology of the cell 25, 2220-34. PMID: 24899641

참고사항

For research use only.

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참고 문헌

데이터시트

Anti-Human OS9 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human OS9 Polyclonal Antibody (HC357014)

개요

이미지

참고 문헌

데이터시트

SDS