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| 카탈로그 번호 | HP434013 | ||||
|---|---|---|---|---|---|
| 설명 |
Anti-Human oxLDL Recombinant Antibody (SAA0551) (HP434013) is a human monoclonal antibody detecting oxLDL in ELISA. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||
| 응용 분야 | ELISA | ||||
| 숙주 종 | Human | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG1, lambda | ||||
| 클론 ID | SAA0551 | ||||
| 타겟 | oxidised LDL, oxidised form of low-density lipoprotein (LDL), oxidised low-density lipoproteins, oxidized low-density lipoprotein, oxidized low-density lipoproteins, OxLDL | ||||
| 내독소 수준 | < 10 EU/mg as determined by LAL method. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| RRID | Anti-Human oxLDL Antibody (SAA0551) (abinScience Cat# HP434013, RRID:AB_3726075) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Adenosine 3', 5'-cyclic monophosphate (cAMP) is a key second messenger molecule in intracellular signal transduction. Monitoring cAMP levels is one of the most common ways to screen for agonists and antagonists of G protein–coupled receptors(GPCRs). Bioyeargene cAMP ELISA Kit is based on the competition between HRP-labeled cAMP and free cAMP for fixed amounts of mouse monoclonal anti-cAMP antibody(cAMP MAb) binding sites. Because the concentration of the HRP-labeled cAMP is held constant while the concentration of cAMP varies, the amount of HRP-labeled cAMP that is able to bind to the cAMP MAb will be inversely proportional to the concentration of cAMP in the well. This antigen-antibody complex binds to the goat anti-mouse IgG that has been previously attached to the well. The plate is washed to remove any unbound reagents and then developed. The ELISA typically displays an IC50(50% B/B0) of approximately 12 pmol/mL and a detection limit of approximately 0.15 pmol/mL. • Sphingosine 1-phosphate: Lipid signaling in pathology and therapy., PMID:31624181 • Sphingosine-1-phosphate (S1P) in ovarian physiology and disease., PMID:31455516 • Sphingosine-1-phosphate (S1P) receptors: Promising drug targets for treating bone-related diseases., PMID:32155312 • Pancreatic Acinar Cells-Derived Sphingosine-1-Phosphate Contributes to Fibrosis of Chronic Pancreatitis via Inducing Autophagy and Activation of Pancreatic Stellate Cells., PMID:37634735 • Significance of sphingosine-1-phosphate in cardiovascular physiology and pathology., PMID:32278039 • Sphingosine 1-Phosphate (S1P)/ S1P Receptor Signaling and Mechanotransduction: Implications for Intrinsic Tissue Repair/Regeneration., PMID:31703256 • Sphingosine 1-phosphate (S1P) receptor modulators as an induction and maintenance therapy for ulcerative colitis: a systematic review and meta-analysis of randomized controlled trials., PMID:38153524 • S1P (Sphingosine-1-Phosphate)-Induced Vasodilation in Human Resistance Arterioles During Health and Disease., PMID:36070401 • Sphingosine 1-phosphate (S1P) signalling: Role in bone biology and potential therapeutic target for bone repair., PMID:28855094 • Sphingosine 1-phosphate signalling., PMID:24346695 | ||||
| 참고사항 | For research use only. | ||||
| Isotype Control | Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507) |
SDS-PAGE for Anti-Human oxLDL Antibody (SAA0551).
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