Anti-Human PCGF6 Polyclonal Antibody (HC219014)

Name: Anti-Human PCGF6 Polyclonal Antibody
Brand: abinScience
SKU: HC219014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HC219014

설명

Anti-Human PCGF6 Polyclonal Antibody (HC219014) is a rabbit polyclonal antibody detecting PCGF6. Suitable for Mouse, Rat, and Human.

Highlights

●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human PCGF6 (Asp252-Thr350).

타겟

MBLR, Mel18 and Bmi1-like RING finger, PCGF6, Polycomb group RING finger protein 6, RING finger protein 134, RNF134

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

Q9BYE7

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

Polycomb group RING finger protein 6 (PCGF6) is a ~39 kDa protein. Transcriptional repressor. May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Within the PRC1-like complex, regulates RNF2 ubiquitin ligase activity.

1. Akasaka, T. et al. (2002) Genes to cells : devoted to molecular & cellular mechanisms 7, 835-50. PMID: 12167161

2. Lee, MG. et al. (2007) Cell 128, 877-87. PMID: 17320162

3. Taherbhoy, AM. et al. (2015) Nature communications 6, 7621. PMID: 26151332

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-Human PCGF6 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human PCGF6 Polyclonal Antibody (HC219014)

개요

이미지

참고 문헌

데이터시트

SDS