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| 카탈로그 번호 | HF902013 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Human | ||||
| 응용 분야 | ELISA, WB | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a, kappa | ||||
| 클론 ID | SAA1521 | ||||
| 타겟 | CRLR activity-modifying protein 2, RAMP2, Calcitonin-receptor-like receptor activity-modifying protein 2, Receptor activity-modifying protein 2 | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | O60895 | ||||
| RRID | Anti-Human RAMP2 Antibody (SAA1521) (abinScience Cat# HF902013, RRID:AB_3727282) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Receptor activity-modifying protein 2 (RAMP2) is a ~19 kDa protein. Accessory protein that interacts with and modulates the function of G-protein coupled receptors including calcitonin gene-related peptide type 1 receptor (CALCRL) and calcitonin receptor (CALCR). Required for the transport of CALCRL to the plasma membrane. Together with CALCRL, form a receptor complex for adrenomedullin/ADM. Together with CALCR, act as a receptor complex for calcitonin/CT/CALC. Together with CALCR, also act as a receptor complex for amylin/IAPP. 1. McLatchie, LM. et al. (1998) Nature 393, 333-9. PMID: 9620797 2. Kusano, S. et al. (2012) Protein science : a publication of the Protein Society 21, 199-210. PMID: 22102369 3. Liang, YL. et al. (2020) ACS pharmacology & translational science 3, 263-284. PMID: 32296767 4. Cao, J. et al. (2022) Science (New York, N.Y.) 375, eabm9609. PMID: 35324283 | ||||
| 참고사항 | For research use only. | ||||
| Isotype Control | Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023) |
SDS-PAGE for Anti-Human RAMP2 Antibody (SAA1521).
Detects recombinant human RAMP2 in indirect ELISA
Western blot analysis was performed using anti-/ monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human RAMP2
Lane 2: negative control
Lane 3: negative control
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