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Anti-Human RAMP2 Recombinant Antibody (SAA2366) (HF902023)

Anti-Human RAMP2 Recombinant Antibody (SAA2366)
Anti-Human RAMP2 Recombinant Antibody (SAA2366)
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Overview
Catalog No.HF902023
Species reactivityHuman
ApplicationsELISA, WB
Host speciesMouse
IsotypeIgG2a, kappa
Clone IDSAA2366
Clonality Monoclonal
Target Receptor activity-modifying protein 2, Calcitonin-receptor-like receptor activity-modifying protein 2, CRLR activity-modifying protein 2, RAMP2
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession O60895
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Receptor activity-modifying protein 2 (RAMP2) is a ~19 kDa protein. Accessory protein that interacts with and modulates the function of G-protein coupled receptors including calcitonin gene-related peptide type 1 receptor (CALCRL) and calcitonin receptor (CALCR). Required for the transport of CALCRL to the plasma membrane. Together with CALCRL, form a receptor complex for adrenomedullin/ADM. Together with CALCR, act as a receptor complex for calcitonin/CT/CALC. Together with CALCR, also act as a receptor complex for amylin/IAPP.

1. McLatchie, LM. et al. (1998) Nature 393, 333-9. PMID: 9620797
2. Kusano, S. et al. (2012) Protein science : a publication of the Protein Society 21, 199-210. PMID: 22102369
3. Liang, YL. et al. (2020) ACS pharmacology & translational science 3, 263-284. PMID: 32296767
4. Cao, J. et al. (2022) Science (New York, N.Y.) 375, eabm9609. PMID: 35324283
Note For research use only
Images
  • Anti-Human RAMP2 Recombinant Antibody (SAA2366)

    Western blot

    Western blot analysis was performed using anti-/ monoclonal antibody at 1ug/mL on various samples.
    Lane 1: recombinant human RAMP2
    Lane 2: negative control
    Lane 3: negative control

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
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Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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C₂ (Working Conc.)
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