

| 카탈로그 번호 | HA495014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human RDH12 Polyclonal Antibody (HA495014) is a rabbit polyclonal antibody detecting RDH12 in ELISA, IHC, WB. Suitable for Bovine, Mus musculus, and Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human RDH12 (Thr33-Glu316). | ||||||||
| 타겟 | RDH12 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q96NR8 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 대체 이름 | Retinol dehydrogenase 12, 1.1.1.300, All-trans and 9-cis retinol dehydrogenase, Short chain dehydrogenase/reductase family 7C member 2, RDH12, SDR7C2 | ||||||||
| 배경 | Retinol dehydrogenase 12 (RDH12) is a ~35 kDa protein. Retinoids dehydrogenase/reductase with a clear preference for NADP. Displays high activity towards 9-cis, 11-cis and all-trans-retinal. Shows very weak activity towards 13-cis-retinol. Also exhibits activity, albeit with lower affinity than for retinaldehydes, towards lipid peroxidation products (C9 aldehydes) such as 4-hydroxynonenal and trans-2-nonenal. May play an important function in photoreceptor cells to detoxify 4-hydroxynonenal and potentially other toxic aldehyde products resulting from lipid peroxidation. 1. Haeseleer, F. et al. (2002) The Journal of biological chemistry 277, 45537-45546. PMID: 12226107 2. Belyaeva, OV. et al. (2005) Biochemistry 44, 7035-47. PMID: 15865448 3. Marchette, LD. et al. (2010) Free radical biology & medicine 48, 16-25. PMID: 19686838 | ||||||||
| 참고사항 | For research use only. |
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