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| 카탈로그 번호 | HX930117 |
|---|---|
| 브랜드 | abinScience |
| 종 반응성 | Human, Mouse, Monkey |
| 응용 분야 | ELISA, FCM |
| 숙주 종 | Mouse |
| 클론성 | Monoclonal |
| 이소타입 | IgG1, kappa |
| 클론 ID | GK-5A1 |
| 접합 | FITC |
| 타겟 | ROR2, Neurotrophic tyrosine kinase, receptor-related 2, NTRKR2, Tyrosine-protein kinase transmembrane receptor ROR2 |
| 내독소 수준 | Please contact with the lab for this information. |
| 관련 제품 | Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), FITC |
| 등록번호 | Q01974 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| 배경 | Tyrosine-protein kinase transmembrane receptor ROR2 (NTRKR2) is a ~104 kDa protein. Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation. In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling. 1. Liu, Y. et al. (2007) Molecular endocrinology (Baltimore, Md.) 21, 3050-61. PMID: 17717073 2. Bainbridge, TW. et al. (2014) PloS one 9, e102695. PMID: 25029443 |
| 참고사항 | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |
Flow-cytometry FITC using anti-human ROR2 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an FITC anti-human ROR2 monoclonal antibody (Catalog HX930117) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.
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