

| 카탈로그 번호 | HD570014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human SLC6A2 NAT1 NET1 SLC6A5 Polyclonal Antibody (HD570014) is a rabbit polyclonal antibody detecting SLC6A2. Suitable for Human.
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human SLC6A2 NAT1 NET1 SLC6A5 (Phe167-Pro233&Ser363-Thr402&Pro570-Ile617). | ||||||||
| 타겟 | NAT1, NET, NET1, Norepinephrine transporter, SLC6A2, SLC6A5, Sodium-dependent noradrenaline transporter, Solute carrier family 6 member 2 | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P23975 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 배경 | Sodium-dependent noradrenaline transporter (SLC6A2 NAT1 NET1 SLC6A5) is a ~69 kDa protein. Mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline), the primary signaling neurotransmitter in the autonomic sympathetic nervous system. Is responsible for norepinephrine re-uptake and clearance from the synaptic cleft, thus playing a crucial role in norepinephrine inactivation and homeostasis. Can also mediate sodium- and chloride-dependent transport of dopamine. 1. Pacholczyk, T. et al. (1991) Nature 350, 350-4. PMID: 2008212 2. Gu, H. et al. (1994) The Journal of biological chemistry 269, 7124-30. PMID: 8125921 3. Zhang, H. et al. (2024) Nature 630, 247-254. PMID: 38750358 4. Syringas, M. et al. (2000) Molecular pharmacology 58, 1404-11. PMID: 11093780 5. Brown, CR. et al. (2025) Journal of neurochemistry 169, e16241. PMID: 39395208 6. Tan, J. et al. (2024) Nature 632, 921-929. PMID: 39048818 | ||||||||
| 참고사항 | For research use only |
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