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Anti-Human SLC6A2 NAT1 NET1 SLC6A5 Polyclonal Antibody (HD570014)

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개요
카탈로그 번호HD570014
설명
Anti-Human SLC6A2 NAT1 NET1 SLC6A5 Polyclonal Antibody (HD570014) is a rabbit polyclonal antibody detecting SLC6A2. Suitable for Human.
종 반응성Human
응용 분야ELISA, IHC, WB
숙주 종Rabbit
클론성Polyclonal
이소타입IgG
면역원 E. coli - derived recombinant Human SLC6A2 NAT1 NET1 SLC6A5 (Phe167-Pro233&Ser363-Thr402&Pro570-Ile617).
타겟 NAT1, NET, NET1, Norepinephrine transporter, SLC6A2, SLC6A5, Sodium-dependent noradrenaline transporter, Solute carrier family 6 member 2
내독소 수준 Please contact with the lab for this information.
정제 Purified by antigen affinity column.
등록번호 P23975
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보
응용 분야 희석
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
배경

Sodium-dependent noradrenaline transporter (SLC6A2 NAT1 NET1 SLC6A5) is a ~69 kDa protein. Mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline), the primary signaling neurotransmitter in the autonomic sympathetic nervous system. Is responsible for norepinephrine re-uptake and clearance from the synaptic cleft, thus playing a crucial role in norepinephrine inactivation and homeostasis. Can also mediate sodium- and chloride-dependent transport of dopamine.

1. Pacholczyk, T. et al. (1991) Nature 350, 350-4. PMID: 2008212
2. Gu, H. et al. (1994) The Journal of biological chemistry 269, 7124-30. PMID: 8125921
3. Zhang, H. et al. (2024) Nature 630, 247-254. PMID: 38750358
4. Syringas, M. et al. (2000) Molecular pharmacology 58, 1404-11. PMID: 11093780
5. Brown, CR. et al. (2025) Journal of neurochemistry 169, e16241. PMID: 39395208
6. Tan, J. et al. (2024) Nature 632, 921-929. PMID: 39048818
참고사항 For research use only
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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