Anti-Human SMARCA2 Polyclonal Antibody (HW576014)

Name: Anti-Human SMARCA2 Polyclonal Antibody
Brand: abinScience
SKU: HW576014
Price: 168 USD
Availability: InStock

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100ug

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HW576014

설명

Anti-Human SMARCA2 Polyclonal Antibody (HW576014) is a rabbit polyclonal antibody detecting SMARCA2. Suitable for Human, Rat, and Mouse.

Highlights

●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human SMARCA2 (Lys725-Ser1179).

타겟

BAF190B, BRG1-associated factor 190B, BRM, EC:3.6.4.-, Probable global transcription activator SNF2L2, Protein brahma homolog, SAMRCA2, SMARCA2, SNF2-alpha, SNF2A, SNF2L2, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2, hBRM

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

P51531

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 (SMARCA2) is a ~181 kDa protein. ATPase involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Binds DNA non-specifically. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state.

1. Liu, K. et al. (2004) Genes & development 18, 673-86. PMID: 15075294

2. Euskirchen, G. et al. (2012) The Journal of biological chemistry 287, 30897-905. PMID: 22952240

3. Kadoch, C. et al. (2015) Science advances 1, e1500447. PMID: 26601204

참고사항

For research use only

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참고 문헌

데이터시트

Anti-Human SMARCA2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human SMARCA2 Polyclonal Antibody (HW576014)

개요

이미지

참고 문헌

데이터시트

SDS