Anti-Human SOX13 Polyclonal Antibody (HP231014)

Name: Anti-Human SOX13 Polyclonal Antibody
Brand: abinScience
SKU: HP231014
Price: 168 USD
Availability: InStock

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50ug
100ug

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HP231014

설명

Anti-Human SOX13 Polyclonal Antibody (HP231014) is a rabbit polyclonal antibody detecting SOX13 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human SOX13 (Asn429-Asp490).

타겟

Islet cell antigen 12, Type 1 diabetes autoantigen ICA12, SRY (Sex determining region Y)-box 13, SOX13, Transcription factor SOX-13

정제

Purified by antigen affinity column.

등록번호

Q9UN79

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Transcription factor SOX-13 (SOX13) is a ~69 kDa protein. Transcription factor that binds to DNA at the consensus sequence 5'-AACAAT-3'. Binds to the proximal promoter region of the myelin protein MPZ gene, and may thereby be involved in the differentiation of oligodendroglia in the developing spinal tube. Binds to the gene promoter of MBP and acts as a transcriptional repressor. Binds to and modifies the activity of TCF7/TCF1, thereby inhibiting transcription and modulates normal gamma-delta T-cell development and differentiation of IL17A expressing gamma-delta T-cells. Regulates expression of BLK in the differentiation of IL17A expressing gamma-delta T-cells.

1. Kasimiotis, H. et al. (2000) Diabetes 49, 555-61. PMID: 10871192

2. Marfil, V. et al. (2010) The Journal of biological chemistry 285, 5726-37. PMID: 20028982

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Human SOX13 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human SOX13 Polyclonal Antibody (HP231014)

개요

이미지

참고 문헌

데이터시트

SDS