Human SOX13 Recombinant Protein (N-GST & C-His) (HP231022)

Name: Human SOX13 Recombinant Protein (N-GST & C-His)
Brand: abinScience
SKU: HP231022
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HP231022
Description	Recombinant Human SOX13 Protein, N-GST & C-His (HP231022) expressed in E. coli, spanning Asn429-Asp490. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	Q9UN79
Protein length	Asn429-Asp490
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	35.69 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Islet cell antigen 12, SOX13, SRY (Sex determining region Y)-box 13, Transcription factor SOX-13, Type 1 diabetes autoantigen ICA12
Background	Transcription factor SOX-13 is a ~69 kDa protein. Transcription factor that binds to DNA at the consensus sequence 5'-AACAAT-3'. Binds to the proximal promoter region of the myelin protein MPZ gene, and may thereby be involved in the differentiation of oligodendroglia in the developing spinal tube. Binds to the gene promoter of MBP and acts as a transcriptional repressor. Binds to and modifies the activity of TCF7/TCF1, thereby inhibiting transcription and modulates normal gamma-delta T-cell development and differentiation of IL17A expressing gamma-delta T-cells. Regulates expression of BLK in the differentiation of IL17A expressing gamma-delta T-cells. 1. Kasimiotis, H. et al. (2000) Diabetes 49, 555-61. PMID: 10871192 2. Marfil, V. et al. (2010) The Journal of biological chemistry 285, 5726-37. PMID: 20028982
Note	For research use only

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Datasheet

Human SOX13 Recombinant Protein (N-GST & C-His).pdf

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Human SOX13 Recombinant Protein (N-GST & C-His) (HP231022)

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