Anti-Human SOX13 Polyclonal Antibody (HP231014)

Name: Anti-Human SOX13 Polyclonal Antibody
Brand: abinScience
SKU: HP231014
Price: 168 USD
Availability: InStock

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Overview
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SDS

Overview

Catalog No.

HP231014

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human SOX13 (Asn429-Asp490).

Target

Islet cell antigen 12, Type 1 diabetes autoantigen ICA12, SRY (Sex determining region Y)-box 13, SOX13, Transcription factor SOX-13

Purification

Purified by antigen affinity column.

Accession

Q9UN79

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Transcription factor SOX-13 (SOX13) is a ~69 kDa protein. Transcription factor that binds to DNA at the consensus sequence 5'-AACAAT-3'. Binds to the proximal promoter region of the myelin protein MPZ gene, and may thereby be involved in the differentiation of oligodendroglia in the developing spinal tube. Binds to the gene promoter of MBP and acts as a transcriptional repressor. Binds to and modifies the activity of TCF7/TCF1, thereby inhibiting transcription and modulates normal gamma-delta T-cell development and differentiation of IL17A expressing gamma-delta T-cells. Regulates expression of BLK in the differentiation of IL17A expressing gamma-delta T-cells.

1. Kasimiotis, H. et al. (2000) Diabetes 49, 555-61. PMID: 10871192

2. Marfil, V. et al. (2010) The Journal of biological chemistry 285, 5726-37. PMID: 20028982

Note

For research use only.

Images

References

Datasheet

Anti-Human SOX13 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human SOX13 Polyclonal Antibody (HP231014)

Overview

Images

References

Datasheet

SDS

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