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| 카탈로그 번호 | HF743025 |
|---|---|
| 설명 |
Anti-Human TG/Thyroglobulin Monoclonal Antibody (1A306) [1A306] (HF743025) is a mouse monoclonal antibody detecting Thyroglobulin in ELISA. Suitable for Human.
|
| 종 반응성 | Human |
| 응용 분야 | ELISA |
| 숙주 종 | Mouse |
| 클론성 | Monoclonal |
| 이소타입 | IgG |
| 클론 ID | 1A306 |
| 면역원 | Human TG/Thyroglobulin Protein. |
| 타겟 | Thyroglobulin, Tg, TG |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >95% as determined by SDS-PAGE. |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | P01266 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 배경 | Thyroglobulin (TG) is a ~304 kDa protein. Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). The synthesis of T3 and T4 involves iodination of selected tyrosine residues of TG/thyroglobulin followed by their oxidative coupling in the thyroid follicle lumen. Following TG re-internalization and lysosomal-mediated proteolysis, T3 and T4 are released from the polypeptide backbone leading to their secretion into the bloodstream. One dimer produces 7 thyroid hormone molecules. 1. Caputo, M. et al. (2007) Clinical endocrinology 67, 351-7. PMID: 17532758 2. Coscia, F. et al. (2020) Nature 578, 627-630. PMID: 32025030 |
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Human TG/Thyroglobulin Monoclonal Antibody (1A306)
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