

| Catalog No. | HF743015 |
|---|---|
| Description |
Anti-Human TG/Thyroglobulin Monoclonal Antibody (1A305) [1A305] (HF743015) is a mouse monoclonal antibody detecting Thyroglobulin in ELISA. Suitable for Human.
|
| Species reactivity | Human |
| Applications | ELISA |
| Host species | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG |
| Clone ID | 1A305 |
| Immunogen | Human TG/Thyroglobulin Protein. |
| Target | Thyroglobulin, Tg, TG |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | P01266 |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Background | Thyroglobulin (TG) is a ~304 kDa protein. Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). The synthesis of T3 and T4 involves iodination of selected tyrosine residues of TG/thyroglobulin followed by their oxidative coupling in the thyroid follicle lumen. Following TG re-internalization and lysosomal-mediated proteolysis, T3 and T4 are released from the polypeptide backbone leading to their secretion into the bloodstream. One dimer produces 7 thyroid hormone molecules. 1. Caputo, M. et al. (2007) Clinical endocrinology 67, 351-7. PMID: 17532758 2. Coscia, F. et al. (2020) Nature 578, 627-630. PMID: 32025030 |
| Note | For research use only. |

SDS-PAGE for Anti-Human TG/Thyroglobulin Monoclonal Antibody (1A305)




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