

| 카탈로그 번호 | HT456014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human TIMM8A Polyclonal Antibody (HT456014) is a rabbit polyclonal antibody detecting TIMM8A in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human TIMM8A (Asp16-Asp97). | ||||||||
| 타겟 | X-linked deafness dystonia protein, TIMM8A, Deafness dystonia protein 1, DDP, TIM8A, DDP1, Mitochondrial import inner membrane translocase subunit Tim8 A | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | O60220 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Mitochondrial import inner membrane translocase subunit Tim8 A (TIMM8A) is a ~10 kDa protein. Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins. Probably necessary for normal neurologic development. | ||||||||
| 참고사항 | For research use only. |
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