Human TIMM8A Recombinant Protein (N-GST & C-His) (HT456022)

Name: Human TIMM8A Recombinant Protein (N-GST & C-His)
Brand: abinScience
SKU: HT456022
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HT456022
Description	Recombinant Human TIMM8A Protein, N-GST & C-His (HT456022) expressed in E. coli, spanning Asp16-Asp97. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	O60220
Protein length	Asp16-Asp97
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	37.87 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	DDP, DDP1, Deafness dystonia protein 1, Mitochondrial import inner membrane translocase subunit Tim8 A, TIM8A, TIMM8A, X-linked deafness dystonia protein
Background	Mitochondrial import inner membrane translocase subunit Tim8 A is a ~10 kDa protein. Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins. Probably necessary for normal neurologic development.
Note	For research use only

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Datasheet

Human TIMM8A Recombinant Protein (N-GST & C-His).pdf

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Human TIMM8A Recombinant Protein (N-GST & C-His) (HT456022)

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