Anti-Human TRIM37 Polyclonal Antibody (HF616014)

Name: Anti-Human TRIM37 Polyclonal Antibody
Brand: abinScience
SKU: HF616014
Price: 168 USD
Availability: InStock

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개요
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개요

카탈로그 번호

HF616014

설명

Anti-Human TRIM37 Polyclonal Antibody (HF616014) is a rabbit polyclonal antibody detecting TRIM37 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human TRIM37 (Ser275-Ser405).

타겟

E3 ubiquitin-protein ligase TRIM37, 2.3.2.27, Mulibrey nanism protein, RING-type E3 ubiquitin transferase TRIM37, Tripartite motif-containing protein 37, TRIM37, KIAA0898, MUL, POB1

정제

Purified by antigen affinity column.

등록번호

O94972

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

E3 ubiquitin-protein ligase TRIM37 is a ~107 kDa protein. E3 ubiquitin-protein ligase required to prevent centriole reduplication. Probably acts by ubiquitinating positive regulators of centriole reduplication. Mediates monoubiquitination of 'Lys-119' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression: associates with some Polycomb group (PcG) multiprotein PRC2-like complex and mediates repression of target genes. Also acts as a positive regulator of peroxisome import by mediating monoubiquitination of PEX5 at 'Lys-472': monoubiquitination promotes PEX5 stabilitation by preventing its polyubiquitination and degradation by the proteasome. Has anti-HIV activity.

1. Kallijärvi, J. et al. (2005) Experimental cell research 308, 146-55. PMID: 15885686

2. Balestra, FR. et al. (2013) Developmental cell 25, 555-71. PMID: 23769972

3. Bhatnagar, S. et al. (2014) Nature 516, 116-20. PMID: 25470042

4. Wang, W. et al. (2017) The Journal of cell biology 216, 2843-2858. PMID: 28724525

5. Tabah, AA. et al. (2014) The Journal of general virology 95, 960-967. PMID: 24317724

참고사항

For research use only.

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참고 문헌

데이터시트

Anti-Human TRIM37 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human TRIM37 Polyclonal Antibody (HF616014)

개요

이미지

참고 문헌

데이터시트

SDS