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| 카탈로그 번호 | HV711013 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Human | ||||
| 응용 분야 | ELISA | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a, kappa | ||||
| 클론 ID | SAA1705 | ||||
| 타겟 | VR1, Vanilloid receptor 1, Transient receptor potential cation channel subfamily V member 1, Capsaicin receptor, Osm-9-like TRP channel 1, TrpV1, TRPV1, OTRPC1 | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | Q8NER1 | ||||
| RRID | Anti-Human TRPV1 Antibody (SAA1705) (abinScience Cat# HV711013, RRID:AB_3727466) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Transient receptor potential cation channel subfamily V member 1 (TRPV1) is a ~94 kDa protein. Non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. Involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Activated by vanilloids, like capsaicin, and temperatures higher than 42 degrees Celsius. 1. Hayes, P. et al. (2000) Pain 88, 205-215. PMID: 11050376 2. Cortright, DN. et al. (2001) Biochemical and biophysical research communications 281, 1183-9. PMID: 11243859 3. McIntyre, P. et al. (2001) British journal of pharmacology 132, 1084-94. PMID: 11226139 4. Smith, GD. et al. (2002) Nature 418, 186-90. PMID: 12077606 5. Neuberger, A. et al. (2023) Nature communications 14, 2451. PMID: 37117175 | ||||
| 참고사항 | For research use only. | ||||
| Isotype Control | Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023) |
SDS-PAGE for Anti-Human TRPV1 Antibody (SAA1705)
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