Anti-Human TSPAN1 Polyclonal Antibody (HT497014)

Name: Anti-Human TSPAN1 Polyclonal Antibody
Brand: abinScience
SKU: HT497014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HT497014

설명

Anti-Human TSPAN1 Polyclonal Antibody (HT497014) is a rabbit polyclonal antibody detecting TSPAN1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human TSPAN1 (Tyr110-Asn211).

타겟

Tetraspanin-1, Tspan-1, Tetraspan NET-1, Tetraspanin TM4-C, TSPAN1

정제

Purified by antigen affinity column.

등록번호

O60635

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Tetraspanin-1 (TSPAN1) is a ~26 kDa protein. Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Participates thereby in diverse biological functions such as cell signal transduction, adhesion, migration and protein trafficking. Regulates neuronal differentiation in response to NGF by facilitating NGF-mediated activation of NTRK1/TRKA receptor tyrosine kinase and subsequent downstream signaling pathways. Plays a role in the inhibition of TNFalpha-induced apoptosis. Mechanistically, inhibits the NF-kappa-B signaling pathway by blocking phosphorylation of CHUK.

1. Tian, J. et al. (2018) Molecular medicine reports 18, 3280-3288. PMID: 30066932

2. Yang, L. et al. (2018) Inflammation research : official journal of the European Histamine Research Society ... [et al.] 67, 951-964. PMID: 30291375

3. Nabokina, SM. et al. (2011) American journal of physiology. Gastrointestinal and liver physiology 301, G808-13. PMID: 21836059

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Human TSPAN1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human TSPAN1 Polyclonal Antibody (HT497014)

개요

이미지

참고 문헌

데이터시트

SDS

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