Anti-Human UCP3 Polyclonal Antibody (HX158014)

Name: Anti-Human UCP3 Polyclonal Antibody
Brand: abinScience
SKU: HX158014
Price: 96 USD
Availability: InStock

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개요
이미지
참고 문헌
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SDS

개요

카탈로그 번호

HX158014

설명

Anti-Human UCP3 Polyclonal Antibody (HX158014) is a rabbit polyclonal antibody detecting UCP3 in ELISA, IHC, WB. Suitable for Rattus norvegicus, Mus musculus, Human, Sus scrofa, and Bovine.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human UCP3 (Met1-Phe312).

타겟

UCP3

정제

Purified by antigen affinity column.

등록번호

P55916

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

대체 이름

Mitochondrial uncoupling protein 3, UCP 3, Solute carrier family 25 member 9, UCP3, SLC25A9

배경

Putative mitochondrial transporter UCP3 is a ~34 kDa protein. Putative transmembrane transporter that plays a role in mitochondrial metabolism via an as yet unclear mechanism. Originally, this mitochondrial protein was thought to act as a proton transmembrane transporter from the mitochondrial intermembrane space into the matrix, causing proton leaks through the inner mitochondrial membrane, thereby uncoupling mitochondrial membrane potential generation from ATP synthesis. However, this function is controversial and uncoupling may not be the function, or at least not the main function, but rather a consequence of more conventional metabolite transporter activity.

1. De Marchi, U. et al. (2011) The Journal of biological chemistry 286, 32533-41. PMID: 21775425

2. Codella, R. et al. (2023) FEBS letters 597, 309-319. PMID: 36114012

3. Echtay, KS. et al. (2001) Proceedings of the National Academy of Sciences of the United States of America 98, 1416-21. PMID: 11171965

4. Zackova, M. et al. (2003) The Journal of biological chemistry 278, 20761-9. PMID: 12670931

5. Jaburek, M. et al. (2003) The Journal of biological chemistry 278, 25825-31. PMID: 12734183

6. Gong, DW. et al. (1997) The Journal of biological chemistry 272, 24129-32. PMID: 9305858

7. Cadenas, S. et al. (2002) The Journal of biological chemistry 277, 2773-8. PMID: 11707458

참고사항

For research use only.

이미지

Western blot

Western blot analysis was performed using anti-UCP3 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse liver lysate
Lane 2: Mouse heart lysate
Lane 3: Rat liver lysate
Lane 4: Rat heart lysate

참고 문헌

데이터시트

Anti-Human UCP3 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human UCP3 Polyclonal Antibody (HX158014)

개요

이미지

참고 문헌

데이터시트

SDS