Anti-Human USP48 Polyclonal Antibody (HB559024)

Name: Anti-Human USP48 Polyclonal Antibody
Brand: abinScience
SKU: HB559024
Price: 168 USD
Availability: InStock

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50ug
100ug

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HB559024

설명

Anti-Human USP48 Polyclonal Antibody (HB559024) is a rabbit polyclonal antibody detecting USP48. Suitable for Human, Rat, and Mouse.

Highlights

●Multi-Species — Cross-reactive for translational research.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human USP48 (Gln423-Val559).

타겟

Deubiquitinating enzyme 48, EC:3.4.19.12, USP31, USP48, Ubiquitin carboxyl-terminal hydrolase 48, Ubiquitin thioesterase 48, Ubiquitin-specific peptidase 48, Ubiquitin-specific protease 48, Ubiquitin-specific-processing protease 48

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

Q86UV5

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

Ubiquitin carboxyl-terminal hydrolase 48 (USP48) is a ~119 kDa protein. Deubiquitinase that recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of polyubiquitin precursors as well as that of ubiquitinated proteins. Plays a role in the regulation of NF-kappa-B activation by TNF receptor superfamily via its interactions with RELA and TRAF2. May also play a regulatory role at postsynaptic sites. Plays an important role in cell cycle progression by deubiquitinating Aurora B/AURKB and thereby extending its stability.

1. Tzimas, C. et al. (2006) Cellular signalling 18, 83-92. PMID: 16214042

2. Bassani, S. et al. (2021) Human molecular genetics 30, 1785-1796. PMID: 34059922

3. Antao, AM. et al. (2021) International journal of molecular sciences 22. PMID: 34445214

4. Jantaree, P. et al. (2022) Cellular and molecular life sciences : CMLS 79, 461. PMID: 35913642

5. Sánchez-Bellver, L. et al. (2022) International journal of molecular sciences 23. PMID: 36293380

6. Ren, Y. et al. (2023) Cancer research 83, 1074-1093. PMID: 36607699

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-Human USP48 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human USP48 Polyclonal Antibody (HB559024)

개요

이미지

참고 문헌

데이터시트

SDS