Human USP48 Recombinant Protein (N-His) (HB559022)

Name: Human USP48 Recombinant Protein (N-His)
Brand: abinScience
SKU: HB559022
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HB559022
Description	Recombinant Human USP48 Protein, N-His (HB559022) expressed in E. coli, spanning Gln423-Val559. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	Q86UV5
Protein length	Gln423-Val559
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	18.15 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Deubiquitinating enzyme 48, EC:3.4.19.12, USP31, USP48, Ubiquitin carboxyl-terminal hydrolase 48, Ubiquitin thioesterase 48, Ubiquitin-specific peptidase 48, Ubiquitin-specific protease 48, Ubiquitin-specific-processing protease 48
Background	Ubiquitin carboxyl-terminal hydrolase 48 is a ~119 kDa protein. Deubiquitinase that recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of polyubiquitin precursors as well as that of ubiquitinated proteins. Plays a role in the regulation of NF-kappa-B activation by TNF receptor superfamily via its interactions with RELA and TRAF2. May also play a regulatory role at postsynaptic sites. Plays an important role in cell cycle progression by deubiquitinating Aurora B/AURKB and thereby extending its stability. 1. Tzimas, C. et al. (2006) Cellular signalling 18, 83-92. PMID: 16214042 2. Bassani, S. et al. (2021) Human molecular genetics 30, 1785-1796. PMID: 34059922 3. Antao, AM. et al. (2021) International journal of molecular sciences 22. PMID: 34445214 4. Jantaree, P. et al. (2022) Cellular and molecular life sciences : CMLS 79, 461. PMID: 35913642 5. Sánchez-Bellver, L. et al. (2022) International journal of molecular sciences 23. PMID: 36293380 6. Ren, Y. et al. (2023) Cancer research 83, 1074-1093. PMID: 36607699
Note	For research use only

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Datasheet

Human USP48 Recombinant Protein (N-His).pdf

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Human USP48 Recombinant Protein (N-His) (HB559022)

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