Anti-Human VAMP8 Polyclonal Antibody (HP094014)

Name: Anti-Human VAMP8 Polyclonal Antibody
Brand: abinScience
SKU: HP094014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HP094014

설명

Anti-Human VAMP8 Polyclonal Antibody (HP094014) is a rabbit polyclonal antibody detecting VAMP8 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human VAMP8 (Glu2-Lys75).

타겟

VAMP8, EDB, Endobrevin, VAMP-8, Vesicle-associated membrane protein 8

정제

Purified by antigen affinity column.

등록번호

Q9BV40

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Vesicle-associated membrane protein 8 (VAMP8) is a ~11 kDa protein. SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t-SNARE complex. Also required for dense-granule secretion in platelets. Also plays a role in regulated enzyme secretion in pancreatic acinar cells.

1. Itakura, E. et al. (2012) Cell 151, 1256-69. PMID: 23217709

2. Diao, J. et al. (2015) Nature 520, 563-6. PMID: 25686604

3. Polgár, J. et al. (2002) Blood 100, 1081-3. PMID: 12130530

4. van Tol, S. et al. (2020) Journal of virology 94. PMID: 31694946

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Human VAMP8 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human VAMP8 Polyclonal Antibody (HP094014)

개요

이미지

참고 문헌

데이터시트

SDS