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| 카탈로그 번호 | VK736033 | ||||||
|---|---|---|---|---|---|---|---|
| 종 반응성 | Influenza A virus (H1N1) | ||||||
| 응용 분야 | ELISA, IF, WB | ||||||
| 숙주 종 | Mouse | ||||||
| 클론성 | Monoclonal | ||||||
| 이소타입 | IgG2a, kappa | ||||||
| 클론 ID | Fab65 | ||||||
| 타겟 | Matrix protein 2, Proton channel protein M2, M | ||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||
| 순도 | >95% as determined by SDS-PAGE. | ||||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||||
| 등록번호 | P06821 | ||||||
| RRID | Anti-Influenza A virus M2 ectodomain/M2e Antibody (Fab65) (abinScience Cat# VK736033, RRID:AB_3729370) |
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| 형태 | Liquid | ||||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||||
| 배경 | Matrix protein 2 is a ~11 kDa protein. Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry. After attaching to the cell surface, the virion enters the cell by endocytosis. Acidification of the endosome triggers M2 ion channel activity. The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur. Also plays a role in viral proteins secretory pathway. | ||||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Influenza A virus M2 ectodomain/M2e Antibody (Fab65)
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