Anti-IQGAP1 Polyclonal Antibody (HC216014)

Name: Anti-IQGAP1 Polyclonal Antibody
Brand: abinScience
SKU: HC216014
Price: 168 USD
Availability: InStock

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사양:

50ug
100ug

수량:

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HC216014

설명

Anti-IQGAP1 Polyclonal Antibody (HC216014) is a rabbit polyclonal antibody detecting IQGAP1. Suitable for Human and Mouse.

Highlights

●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant IQGAP1 (Ser962-Ser1345).

타겟

IQGAP1, KIAA0051, Ras GTPase-activating-like protein IQGAP1, p195

내독소 수준

Please contact with the lab for this information.

관찰된 분자량

190 kDa

정제

Purified by antigen affinity column.

등록번호

P46940

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

재구성

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

배송

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Ras GTPase-activating-like protein IQGAP1 is a ~189 kDa protein. Plays a crucial role in regulating the dynamics and assembly of the actin cytoskeleton. Recruited to the cell cortex by interaction with ILK which allows it to cooperate with its effector DIAPH1 to locally stabilize microtubules and allow stable insertion of caveolae into the plasma membrane. Binds to activated CDC42 but does not stimulate its GTPase activity. Associates with calmodulin. May promote neurite outgrowth.

1. Li, Z. et al. (2005) The Journal of biological chemistry 280, 13871-8. PMID: 15695813

2. Johnson, M. et al. (2011) The international journal of biochemistry & cell biology 43, 65-73. PMID: 20883816

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-IQGAP1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-IQGAP1 Polyclonal Antibody (HC216014)

개요

이미지

참고 문헌

데이터시트

SDS