中文
English
한국어
日本語
Español
Français
Русский
| 카탈로그 번호 | HC627033 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Human, Mouse, Rat | ||||
| 응용 분야 | IHC, WB | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a, kappa | ||||
| 클론 ID | N1/66 | ||||
| 타겟 | CAMKG, CAMK-II, CAMK, CAMK2G, CaM kinase II subunit gamma, CaMK-II subunit gamma, Calcium/calmodulin-dependent protein kinase type II subunit gamma | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | Q63633 | ||||
| RRID | Anti-KCC2 Antibody (N1/66) (abinScience Cat# HC627033, RRID:AB_3728371) |
||||
| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
||||
| 제품 사용 정보 |
| ||||
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Solute carrier family 12 member 5 (SLC12A5/KCC2) is a ~126 kDa protein. Mediates electroneutral potassium-chloride cotransport in mature neurons and is required for neuronal Cl(-) homeostasis. As major extruder of intracellular chloride, it establishes the low neuronal Cl(-) levels required for chloride influx after binding of GABA-A and glycine to their receptors, with subsequent hyperpolarization and neuronal inhibition. Involved in the regulation of dendritic spine formation and maturation. 1. Casula, S. et al. (2001) The Journal of biological chemistry 276, 41870-8. PMID: 11551954 2. Rivera, C. et al. (1999) Nature 397, 251-5. PMID: 9930699 3. Fiumelli, H. et al. (2013) Cerebral cortex (New York, N.Y. : 1991) 23, 378-88. PMID: 22345354 | ||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-KCC2 Antibody (N1/66)
+86-027-65523339
중국 우한시 심둔사로 666번지 C동, 우한, 430206
