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Anti-KCNJ10 Polyclonal Antibody (HX144014)

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개요
카탈로그 번호HX144014
설명
Anti-KCNJ10 Polyclonal Antibody (HX144014) is a rabbit polyclonal antibody detecting KCNJ10 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
종 반응성Human, Mouse, Rat
응용 분야ELISA, IHC, WB
숙주 종Rabbit
클론성Polyclonal
이소타입IgG
면역원 E. coli - derived recombinant Human KCNJ10 (Phe165-Val379).
타겟 ATP-dependent inwardly rectifying potassium channel Kir4.1, KCNJ10, ATP-sensitive inward rectifier potassium channel 10, Inward rectifier K(+) channel Kir1.2, Potassium channel, inwardly rectifying subfamily J member 10
정제 Purified by antigen affinity column.
등록번호 P78508
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보
응용 분야 희석
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
배경

ATP-sensitive inward rectifier potassium channel 10 (KCNJ10) is a ~42 kDa protein. May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium.

1. Shuck, ME. et al. (1997) The Journal of biological chemistry 272, 586-93. PMID: 8995301
2. Tanemoto, M. et al. (2014) FEBS letters 588, 899-905. PMID: 24561201
참고사항 For research use only.
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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