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| 카탈로그 번호 | HC335013 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Human, Mouse, Rat | ||||
| 응용 분야 | IB, ICC, IHC, WB | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a, kappa | ||||
| 클론 ID | K25/73 | ||||
| 타겟 | KCNAB2, hKvbeta2, KCNK2, KCNA2B, Voltage-gated potassium channel subunit beta-2, K(+) channel subunit beta-2, Kv-beta-2 | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | Q13303 | ||||
| RRID | Anti-Kvbeta K+ channel/Pan-Kvbeta K+ channel Antibody (K25/73) (abinScience Cat# HC335013, RRID:AB_3728418) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Voltage-gated potassium channel subunit beta-2 (KCNAB2) is a ~41 kDa protein. Regulatory subunit of the voltage-gated potassium (Kv) Shaker channels composed of pore-forming and potassium-conducting alpha subunits and of regulatory beta subunits. The beta-2/KCNAB2 cytoplasmic subunit promotes potassium channel closure via a mechanism that does not involve physical obstruction of the channel pore. Promotes the inactivation of Kv1.4/KCNA4 and Kv1.5/KCNA5 alpha subunit-containing channels. Displays nicotinamide adenine dinucleotide phosphate (NADPH)-dependent aldoketoreductase activity by catalyzing the NADPH-dependent reduction of a wide range of aldehyde and ketone substrates. Substrate specificity includes methylglyoxal, 9,10-phenanthrenequinone, prostaglandin J2, 4-nitrobenzaldehyde, 4-nitroacetophenone and 4-oxo-trans-2-nonenal (in vitro, no physiological substrate identified yet). 1. McCormack, K. et al. (2002) The Journal of biological chemistry 277, 13219-28. PMID: 11825900 2. McCormack, K. et al. (1995) FEBS letters 370, 32-6. PMID: 7649300 | ||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Kvbeta K+ channel/Pan-Kvbeta K+ channel Antibody (K25/73)
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