Anti-MeV Non-structural protein V Polyclonal Antibody (VK815014)

Name: Anti-MeV Non-structural protein V Polyclonal Antibody
Brand: abinScience
SKU: VK815014
Price: 168 USD
Availability: InStock

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100ug

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

VK815014

설명

Anti-MeV Non-structural protein V Polyclonal Antibody (VK815014) is a rabbit polyclonal antibody detecting Non-structural protein V. Suitable for Measles virus.

종 반응성

Measles virus (MeV)

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant MeV Non-structural protein V (Met1-Gly231).

타겟

Non-structural protein V, P/V

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

P0C774

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

Non-structural protein V is a ~32 kDa protein. Plays an essential role in the inhibition of host immune response. Prevents the establishment of cellular antiviral state by blocking interferon-alpha/beta (IFN-alpha/beta) production and signaling pathway. Interacts with host IFIH1/MDA5 and DHX58/LGP2 to inhibit the transduction pathway involved in the activation of IFN-beta promoter, thus protecting the virus against cell antiviral state. Blocks the type I interferon signaling pathway by interacting with host TYK2 and thereby inhibiting downstream STAT1 and STAT2 phosphorylation. Blocks the type I interferon signaling pathway by disrupting the RIG-I signaling pathway.

1. Takeuchi, K. et al. (2003) FEBS letters 545, 177-82. PMID: 12804771

2. Parisien, JP. et al. (2009) Journal of virology 83, 7252-60. PMID: 19403670

3. Ramachandran, A. et al. (2008) Journal of virology 82, 8330-8. PMID: 18579593

4. Chinnakannan, SK. et al. (2013) PloS one 8, e57063. PMID: 23431397

5. Davis, ME. et al. (2014) Cell host & microbe 16, 19-30. PMID: 25011105

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-MeV Non-structural protein V Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-MeV Non-structural protein V Polyclonal Antibody (VK815014)

개요

이미지

참고 문헌

데이터시트

SDS