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| 카탈로그 번호 | VK796014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-MeV Phosphoprotein Polyclonal Antibody (VK796014) is a rabbit polyclonal antibody detecting Phosphoprotein. Suitable for Measles virus.
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| 종 반응성 | Measles virus (MeV) | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant MeV Phosphoprotein (Gly304-Leu377). | ||||||||
| 타겟 | P/V, Phosphoprotein, Protein P | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q9WMB4 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 배경 | Phosphoprotein is a ~53 kDa protein. Essential cofactor of the RNA polymerase L that plays a central role in the transcription and replication by forming the polymerase complex with RNA polymerase L and recruiting L to the genomic N-RNA template for RNA synthesis. Also plays a central role in the encapsidation of nascent RNA chains by forming the encapsidation complex with the nucleocapsid protein N (N-P complex). Acts as a chaperone for newly synthesized free N protein, so-called N0, allowing encapsidation of nascent RNA chains during replication. The nucleoprotein protein N prevents excessive phosphorylation of P, which leads to down-regulation of viral transcription/ replication. Participates, together with N, in the formation of viral factories (viroplasms), which are large inclusions in the host cytoplasm where replication takes place. 1. Guseva, S. et al. (2020) Science advances 6, eaaz7095. PMID: 32270045 | ||||||||
| 참고사항 | For research use only |
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