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Anti-Mouse CCL17/TARC Polyclonal Antibody (MV615014)

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개요
카탈로그 번호MV615014
설명
Anti-Mouse CCL17/TARC Polyclonal Antibody (MV615014) is a rabbit polyclonal antibody detecting CCL17/TARC in ELISA, IHC, WB. Suitable for Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
종 반응성Mouse
응용 분야ELISA, IHC, WB
숙주 종Rabbit
클론성Polyclonal
이소타입IgG
면역원 E. coli - derived recombinant Mouse CCL17/TARC (Ala24-Pro93).
타겟 C-C motif chemokine 17 (ABCD-2) (CC chemokine TARC) (Small-inducible cytokine A17) (Thymus and activation-regulated chemokine)
내독소 수준 Please contact with the lab for this information.
순도 >95% as determined by SDS-PAGE.
정제 Purified by antigen affinity column.
등록번호 Q9WUZ6
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보
응용 분야 희석
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
배경

C-C motif chemokine 17 (CCL17/TARC) is a ~10 kDa protein. Chemokine, which displays chemotactic activity for T lymphocytes, preferentially Th2 cells, but not monocytes or granulocytes. Therefore plays an important role in a wide range of inflammatory and immunological processes. Acts by binding to CCR4 at T-cell surface. Mediates GM-CSF/CSF2-driven pain and inflammation. In the brain, required to maintain the typical, highly branched morphology of hippocampal microglia under homeostatic conditions.

1. Lieberam, I. et al. (1999) European journal of immunology 29, 2684-94. PMID: 10508243
2. Schaniel, C. et al. (1999) European journal of immunology 29, 2934-47. PMID: 10508268
3. Achuthan, A. et al. (2016) The Journal of clinical investigation 126, 3453-66. PMID: 27525438
4. Fülle, L. et al. (2018) Glia 66, 2246-2261. PMID: 30277599
5. Kato, T. et al. (2011) Experimental dermatology 20, 669-74. PMID: 21521373
참고사항 For research use only.
이미지
참고 문헌
Formula
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Working Solution
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