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| 카탈로그 번호 | MB066014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Mouse CD121b/IL1R2 Polyclonal Antibody (MB066014) is a rabbit polyclonal antibody detecting CD121b. Suitable for Mouse.
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| 종 반응성 | Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Mouse CD121b/IL1R2 (Glu52-Lys241). | ||||||||
| 타겟 | CD121 antigen-like family member B, CD121b, IL-1 type II receptor, IL-1R-2, IL-1R-beta, IL-1RT-2, IL-1RT2, Il-1r2, Il1r2, Il1rb, Interleukin-1 receptor beta, Interleukin-1 receptor type 2, Interleukin-1 receptor type 2, membrane form, Interleukin-1 receptor type 2, soluble form, Interleukin-1 receptor type II, mIL-1R2, mIL-1RII, sIL-1R2, sIL-1RII | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 순도 | >95% as determined by SDS-PAGE. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P27931 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 배경 | Interleukin-1 receptor type 2 (CD121b/IL1R2) is a ~45 kDa protein. Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competitive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. | ||||||||
| 참고사항 | For research use only |
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