

| Catalog No. | MB066012 |
|---|---|
| Description |
Recombinant Mouse CD121b/IL1R2 Protein, N-His (MB066012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Expression system | E. coli |
| Accession | P27931 |
| Protein length | Glu52-Lys241 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Mus musculus (Mouse) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | CD121 antigen-like family member B, CD121b, IL-1 type II receptor, IL-1R-2, IL-1R-beta, IL-1RT-2, IL-1RT2, Il-1r2, Il1r2, Il1rb, Interleukin-1 receptor beta, Interleukin-1 receptor type 2, Interleukin-1 receptor type 2, membrane form, Interleukin-1 receptor type 2, soluble form, Interleukin-1 receptor type II, mIL-1R2, mIL-1RII, sIL-1R2, sIL-1RII |
| Background | Interleukin-1 receptor type 2 is a ~45 kDa protein. Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competitive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. |
| Note | For research use only |
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