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Anti-Mouse CD121b/IL1R2 Polyclonal Antibody (MB066014)

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Overview
Catalog No.MB066014
Description
Anti-Mouse CD121b/IL1R2 Polyclonal Antibody (MB066014) is a rabbit polyclonal antibody detecting CD121b. Suitable for Mouse.
Species reactivityMouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Mouse CD121b/IL1R2 (Glu52-Lys241).
Target CD121 antigen-like family member B, CD121b, IL-1 type II receptor, IL-1R-2, IL-1R-beta, IL-1RT-2, IL-1RT2, Il-1r2, Il1r2, Il1rb, Interleukin-1 receptor beta, Interleukin-1 receptor type 2, Interleukin-1 receptor type 2, membrane form, Interleukin-1 receptor type 2, soluble form, Interleukin-1 receptor type II, mIL-1R2, mIL-1RII, sIL-1R2, sIL-1RII
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession P27931
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Interleukin-1 receptor type 2 (CD121b/IL1R2) is a ~45 kDa protein. Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competitive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN.

Note For research use only
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Anti-Mouse CD121b/IL1R2 Polyclonal Antibody

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