Anti-Mouse CD244 Polyclonal Antibody (MV513014)

Name: Anti-Mouse CD244 Polyclonal Antibody
Brand: abinScience
SKU: MV513014
Price: 96 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

MV513014

설명

Anti-Mouse CD244 Polyclonal Antibody (MV513014) is a rabbit polyclonal antibody detecting CD244 in ELISA, IHC, WB. Suitable for Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Mouse CD244 (Asp24-Thr212).

타겟

SLAM family member 4, SLAMF4, h2B4, Signaling lymphocytic activation molecule 4, Natural killer cell receptor 2B4, NKR2B4, NAIL, NK cell type I receptor protein 2B4, CD244, NK cell activation-inducing ligand, 2B4

정제

Purified by antigen affinity column.

등록번호

Q07763

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Natural killer cell receptor 2B4 (CD244) is a ~44 kDa protein. Heterophilic receptor of the signaling lymphocytic activation molecule (SLAM) family; its ligand is CD48. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Acts as activating natural killer (NK) cell receptor. Activating function implicates association with SH2D1A and FYN.

1. Lee, KM. et al. (2003) Journal of immunology (Baltimore, Md. : 1950) 170, 4881-5. PMID: 12734329

2. Dong, Z. et al. (2009) Nature immunology 10, 973-80. PMID: 19648922

3. Wang, N. et al. (2010) Journal of immunology (Baltimore, Md. : 1950) 185, 5683-7. PMID: 20962259

4. Garni-Wagner, BA. et al. (1993) Journal of immunology (Baltimore, Md. : 1950) 151, 60-70. PMID: 8326140

5. Chen, R. et al. (2004) Molecular and cellular biology 24, 5144-56. PMID: 15169881

6. Bloch-Queyrat, C. et al. (2005) The Journal of experimental medicine 202, 181-92. PMID: 15998796

7. Dong, Z. et al. (2012) Immunity 36, 974-85. PMID: 22683124

8. Lee, KM. et al. (2006) Blood 107, 3181-8. PMID: 15905190

9. Roncagalli, R. et al. (2005) Nature immunology 6, 1002-10. PMID: 16127454

참고사항

For research use only.

이미지

Western blot

Western blot analysis was performed using anti-CD244 polyclonal antibody at 1ug/mL on various samples.
Lane 1: MCF-7 cell lysate

참고 문헌

데이터시트

Anti-Mouse CD244 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Mouse CD244 Polyclonal Antibody (MV513014)

개요

이미지

참고 문헌

데이터시트

SDS

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