Anti-Mouse ABCG2/CD338 Polyclonal Antibody (MV314014)

Name: Anti-Mouse ABCG2/CD338 Polyclonal Antibody
Brand: abinScience
SKU: MV314014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

MV314014

설명

Anti-Mouse CD338/ABCG2 Polyclonal Antibody (MV314014) is a rabbit polyclonal antibody detecting Abcg2. Suitable for Rat and Mouse.

Highlights

●Multi-Species — Cross-reactive for translational research.

종 반응성

Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Mouse CD338/ABCG2 (Asp35-Pro353).

타겟

ATP-binding cassette sub-family G member 2, Abcg2, Abcp, Bcrp1, Breast cancer resistance protein 1 homolog, Broad substrate specificity ATP-binding cassette transporter ABCG2, CD338, EC:7.6.2.2, Urate exporter

내독소 수준

Please contact with the lab for this information.

순도

>95% as determined by SDS-PAGE.

정제

Purified by antigen affinity column.

등록번호

Q7TMS5

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

Broad substrate specificity ATP-binding cassette transporter ABCG2 (CD338) is a ~72 kDa protein. Broad substrate specificity ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes a wide variety of physiological compounds, dietary toxins and xenobiotics from cells. Involved in porphyrin homeostasis, mediating the export of protoporphyrin IX (PPIX) from both mitochondria to cytosol and cytosol to extracellular space, it also functions in the cellular export of heme. Also mediates the efflux of sphingosine-1-P from cells. Acts as a urate exporter functioning in both renal and extrarenal urate excretion. In kidney, it also functions as a physiological exporter of the uremic toxin indoxyl sulfate.

1. Allen, JD. et al. (1999) Cancer research 59, 4237-41. PMID: 10485464

2. Jonker, JW. et al. (2002) Proceedings of the National Academy of Sciences of the United States of America 99, 15649-54. PMID: 12429862

3. Allen, JD. et al. (2002) Molecular cancer therapeutics 1, 417-25. PMID: 12477054

4. van Herwaarden, AE. et al. (2007) Molecular and cellular biology 27, 1247-53. PMID: 17145775

5. Takada, T. et al. (2018) Scientific reports 8, 11147. PMID: 30042379

6. Krishnamurthy, P. et al. (2004) The Journal of biological chemistry 279, 24218-25. PMID: 15044468

7. Millán-García, A. et al. (2024) International journal of molecular sciences 25. PMID: 39337371

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-Mouse ABCG2/CD338 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Mouse ABCG2/CD338 Polyclonal Antibody (MV314014)

개요

이미지

참고 문헌

데이터시트

SDS