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Anti-Mouse CIDEC Polyclonal Antibody (MV727014)

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개요
카탈로그 번호MV727014
설명
Anti-Mouse CIDEC Polyclonal Antibody (MV727014) is a rabbit polyclonal antibody detecting Cidec in ELISA, IHC, WB. Suitable for Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
종 반응성Mouse, Rat
응용 분야ELISA, IHC, WB
숙주 종Rabbit
클론성Polyclonal
이소타입IgG
면역원 E. coli - derived recombinant Mouse CIDEC (Arg41-Cys178).
타겟 Lipid transferase CIDEC, Cell death-inducing DFFA-like effector protein C, Fat-specific protein FSP27, Cidec, Fsp27
정제 Purified by antigen affinity column.
등록번호 P56198
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보
응용 분야 희석
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
배경

Lipid transferase CIDEC is a ~27 kDa protein. Lipid transferase specifically expressed in white adipose tissue, which promotes unilocular lipid droplet formation by mediating lipid droplet fusion. Lipid droplet fusion promotes their enlargement, restricting lipolysis and favoring lipid storage. Localizes on the lipid droplet surface, at focal contact sites between lipid droplets, and mediates atypical lipid droplet fusion by undergoing liquid-liquid phase separation (LLPS) and promoting directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair. Its role in neutral lipid transfer and lipid droplet enlargement is activated by the interaction with PLIN1.

1. Keller, P. et al. (2008) The Journal of biological chemistry 283, 14355-65. PMID: 18334488
2. Gong, J. et al. (2011) The Journal of cell biology 195, 953-63. PMID: 22144693
3. Xu, W. et al. (2016) The Journal of biological chemistry 291, 4282-93. PMID: 26733203
4. Wang, J. et al. (2018) The Journal of biological chemistry 293, 19330-19343. PMID: 30361435
5. Qian, K. et al. (2023) Nature 613, 160-168. PMID: 36477540
6. Toh, SY. et al. (2008) PloS one 3, e2890. PMID: 18682832
참고사항 For research use only.
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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